Semax
NOOTROPIC PEPTIDE — RESEARCH COMPOUND

Semax

ACTH(4-7)PGP — Neuroprotective Heptapeptide

PURITY

99.5%

CAS

80714-61-0

MW

708.82 g/mol

STORAGE

-20°C, lyophilized

COA

COMING SOON

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COMPOUND SPEC SHEET

BATCH AR24-SMX-05
FULL IUPAC NAMEACTH(4-7)PGP — Neuroprotective Heptapeptide
CAS REGISTRY NO.80714-61-0
MOLECULAR FORMULAC₃₃H₄₃N₉O₈S
MOLECULAR WEIGHT708.82 g/mol
CONFIRMED PURITY99.5% (HPLC-MS Third-Party Analysis)
APPEARANCEWhite lyophilized powder, hygroscopic
SOLUBILITYFreely soluble in water; soluble in saline, PBS, DMSO
STORAGE CONDITIONS-20°C, lyophilized
TARGET RECEPTORSMC4R (Melanocortin-4R) | BDNF / TrkB pathway modulator
PLASMA HALF-LIFEApproximately 10–20 minutes in plasma (short, central action)
BATCH IDENTIFIERAR24-SMX-05
AMINO ACID SEQUENCE
Met-Glu-His-Phe-Pro-Gly-Pro
ANALYTICAL PURITY — HPLC CHROMATOGRAMPASS ✔
99.5%
0%100%

TECHNICAL RESEARCH NOTES

01

ACTH(4-7) fragment with Pro-Gly-Pro (PGP) extension significantly increases CNS bioavailability

02

Upregulates BDNF and NGF expression in hippocampal and cortical neuronal cell models

03

Met residue is susceptible to oxidation; consider N2-purged storage vials for maximum stability

04

MC receptor affinity: MC4R > MC3R > MC1R

RECONSTITUTION PROTOCOL

RECOMMENDED SOLVENT

Sterile Saline (0.9% NaCl) or Bacteriostatic Water

STOCK CONCENTRATION

5 mg/mL stock solution

WORKING RANGE

0.1–10 mg/mL depending on assay

STEP-BY-STEP PROCEDURE — CLICK STEP TO EXPAND

STABILITY DATA

Lyophilized: 24 months at −20°C | Reconstituted: 7 days at 4°C (protect from light)

CRITICAL — RESEARCH USE ONLY

This reconstitution protocol is intended solely for qualified research professionals conducting in-vitro laboratory research. This compound is strictly not for human consumption, veterinary use, or any clinical application. All handling must comply with applicable laboratory safety regulations.

SAFETY & COMPLIANCE

IN-VITRO USE ONLY

This compound is exclusively intended for in-vitro laboratory research by qualified scientific professionals in appropriate laboratory settings.

NOT FOR HUMAN USE

Not approved for human consumption, administration, or therapeutic use. Strictly prohibit use in human subjects or veterinary applications.

PROPER PPE REQUIRED

Handle with appropriate personal protective equipment: nitrile gloves, safety glasses, and lab coat. Follow all institutional safety protocols.

COLD-CHAIN REQUIRED

Maintain cold-chain integrity from shipment receipt through storage. Temperature excursions may compromise compound integrity and research validity.

RESEARCH INQUIRY

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EST. REAGENT COST$32
Quantity: 10mg lyophilizedPurity: 99.5%

This compound is temporarily unavailable. Contact us to be notified when it restocks.

Estimated cost for research reagent inquiry only. Not a purchase order. For in-vitro laboratory research use only.

IN-VITRO RESEARCH ONLY
THIRD-PARTY COA VERIFIED
NOT FOR HUMAN CONSUMPTION
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BATCH & CERTIFICATION

Batch IDAR24-SMX-05
Analysis MethodHPLC-MS
Test Date2025-03-03
GradeResearch Grade

CERTIFICATE OF ANALYSIS

PDF coming soon

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